Controlling Collagen organization, 19PaperCon
Controlling surface energy and morphology evolution in paper has been motivated, in part, by the recent interest in frugal innovation – that is extending sustainable technology beyond sourcing and re-use to mitigating cost and complexity in technological advances. Besides these frugal uses, paper presents an affordable approach to engineer surface physics and hence tune biological responses. Herein, we demonstrate classical use of surface energy engineering to make affordable devices but extend these uses to controlling collagen organization. We demonstrate that calendaring and surface modification through polymerization-induced self-assembly to create surface amphiphillicity, leads to a tunable method of controlling collagen organization. We observe that a combination of surface roughness, hydrophobicity alters collagen organization over time.
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Controlling Collagen organization, 19PaperCon